Europe PMC 干细胞论文检索· Zaman A, Holton E, Pandya M, Shillington G, Escher C, Sudhakar KK, Tuzesi A, Mehta A, Lam E, Zekanovic R, Sughrue M, Teo C, Yeung J, Muskovic W, Powell JE.·· 13 天前AI 评分54
单细胞与空间图谱揭示弥漫性胶质瘤中IDH相关的恶性与免疫结构差异
A State-Resolved Single-Cell and Spatial Atlas Reveals IDH -Associated Differences in Malignant and Immune Architecture in Diffuse Glioma.
AI 导读
研究对69例肿瘤进行scRNA-seq、snRNA-seq和空间转录组分析，解析出七种复发性恶性细胞状态：星形细胞样祖细胞（ALPC）、缺氧、G1/S周期、G2/M周期、少突谱系、神经少突谱系和神经谱系。
来源：Europe PMC 干细胞论文检索 · europepmc.org