bioRxiv · Genomics· Toong, P. J., Boushaki, S., Zhao, S. J., Brough, R., Song, F. F., Krastev, D. B., Black, D., Rinaldi, G., Badja, C., Degasperi, A., Czarnecki, J., Memari, Y., Davies, H., Huebschmann, D., Glimm, H., Froehling, S., Tutt, A. N. J., Pettitt, S., Lord, C. J., Koh, G. C., Nik-Zainal, S. ·· 1 天前精选AI 评分60
bioRxiv预印本：核糖核苷酸切除修复缺陷的全基因组突变特征及治疗脆弱性
Global signatures of Ribonucleotide Excision Repair deficiency and its therapeutic vulnerabilities
AI 导读
bioRxiv预印本提出核糖核苷酸切除修复（RER）缺陷会在全基因组层面产生特征性插入缺失、替换和结构变异突变表型，并据此开发出全基因组分类器RERDetect。
来源：bioRxiv · Genomics · biorxiv.org