野火烟雾对美国死亡率留下长达五年的影响印记
Wildfire smoke leaves a large five-year imprint on mortality in the United States
一项基于美国2006至2023年县级月度野火PM2.5与死亡率数据的研究,通过利用暴露脉冲差异反卷积重叠的死亡响应,恢复出脉冲响应函数:超额死亡响应在暴露脉冲后约三年达到峰值,五年内消退。
利用美国县级月度野火PM2.5与死亡数据反卷积出暴露后死亡响应曲线,为评估多年健康负担提供方法参考。
Abstract
Wildfire smoke poses a growing health risk worldwide, yet the magnitude and temporal evolution of mortality after episodic exposure remain poorly resolved, limiting burden assessment. Using monthly county-level wildfire PM2.5 and mortality data from the United State, we exploit episodic exposure contrasts to deconvolve overlapping mortality responses and recover the impulse-response function. The excess mortality response peaks approximately three years after an exposure pulse and subsides by five years. We estimate 1.7 (95% uncertainty interval: 1.1-2.3) million smoke-associated deaths during 2011-2023, approximately ten times estimates using long-term ambient PM2.5 mortality relative risks. Circulatory and respiratory diseases contribute comparably and dominate this burden. Responses are markedly greater among adults ≥65 years; during the COVID-19 pandemic, population-wide cumulative responses are significantly higher over at least the first seven months after exposure. Reducing wildfire smoke exposure can thus yield substantial health benefits over multiple years, particularly when population vulnerability is heightened.
Competing Interest Statement
The authors have declared no competing interest.
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Month-county level mortality data in the contiguous United States (US) from 2006 to 2023 were collected from the CDC (Centers for Disease Control and Prevention) WONDER (Wide-ranging Online Data for Epidemiologic Research) online database. (https://wonder.cdc.gov/)
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The data sources, models, and model configurations underlying the conclusions are described in the main text.
Funder Information Declared
Max Planck Society, https://ror.org/01hhn8329
来源:medRxiv · 临床预印本 · medrxiv.org